Great Ormond Street Hospital for Children NHS Foundation Trust (GOSH) is a national centre of excellence in the provision of specialist children's health care, currently delivering the widest range of specialist care of any children's hospital in the UK. It aspires to offer outcomes for children in the top five in the world. The largest centre in the UK for children with heart or brain problems, and, with UCLH it is the largest centre in Europe for children with cancer. It is the only specialist Biomedical Research Centre for paediatrics, it works in partnership with the UCL Institute of Child Health (ICH), part of University College London, and together they form the largest paediatric research and teaching centre in the UK, and one of the largest in the world. The hospital at Great Ormond Street is the only exclusively specialist children's hospital in the UK. It does not have an Accident and Emergency department and largely only accepts specialist referrals from other hospitals and community services. The population of children served by the hospital is characterised by those with multiple disabilities and/or health problems and rare and congenital (present at birth) conditions.