The Channeling Hope Foundation was started by parents of children with NALCN genetic mutations who connected over a shared hope for a world free of NALCN channel diseases. NALCN (Sodium Leak Channel) diseases are a group of rare genetic disorders that result from mutations in the NALCN gene and associated proteins (UNC79, UNC80, FAM155A). NALCN plays a crucial role in regulating the electrical activity of neurons and other cells. Supported by a global network of NALCN scientists and a small but mighty community of affected families, the Channeling Hope Foundation was established in 2023 to work together to advance care and develop treatments for children affected by NALCN genetic disorders.