The National Blood Service Ghana (NBSG) operates as an agency of the Ministry of Health of Ghana, mandated to ensure access to safe and adequate blood and blood components and related blood services towards the attainment of universal health coverage in Ghana. The NBSG comprise a Headquarters and three zonal Blood Centres in Accra, Kumasi and Tamale. The goal of the NBSG is to attain a sustainable national supply of safe blood that relies on 100 per cent voluntary unpaid blood donations in a manner responsive to the needs of patients requiring blood transfusion therapy in both public and private health institutions in Ghana. The NBSG develops and disseminates guidelines on appropriate clinical use of blood and blood components to prescribers, users and those who manage the administration of blood and blood components in health facilities in Ghana. The NBSG is responsible for the inspection and accreditation of hospital blood banks to receive blood and blood components from Blood Centres for storage and compatibility testing to patients in Ghana. The NBSG operates through a National Blood Policy, which aims to strengthen the National Blood Service to increase access to safe, affordable, and quality blood and blood components and related blood services at the highest attainable standards in Ghana.