The Centre for Genomic Regulation (CRG) is an international biomedical research institute of excellence, created in December 2000. It is a non-profit foundation funded by the Catalan Government through the departments of Economy & Knowledge and Health, the Spanish Ministry of Economy and Competitiveness, "la Caixa" Banking Foundation, and includes the participation of Pompeu Fabra University (UPF). The mission of the CRG is to discover and advance knowledge for the benefit of society, public health and economic prosperity. The CRG believes that the medicine of the future depends on the groundbreaking science of today. This requires an interdisciplinary scientific team focused on understanding the complexity of life from the genome and the cell up to an entire organism and its interaction with the environment, offering an integrated view of genetic diseases. The CRG’s main goals are: a) to be a world-leading centre in biomedical science; b) to communicate and establish a bilateral dialogue with society; c) to provide advanced training for the next generation of scientists; and d) to transform new scientific knowledge into benefits for health and economic value for society.