REMEDY – Center for treatment of Rheumatology and Musculoskeletal Diseases was established in spring 2022 as a new Center for Clinical Treatment Research. Diakonhjemmet hospital is the host institution and the center has four affiliated partners: Oslo University Hospital, University of Oslo, Norwegian Rheumatism Association and the MAGIC foundation. The objective of the REMEDY center is to develop excellent treatment and treatment strategies in rheumatic and musculoskeletal diseases through a broad approach to this field of research. The research is organized into seven work packages with the following themes: 1) Randomized controlled clinical trials testing various aspects of treatment, including drugs, surgery, treatment strategies, physical activity and approaches to decision support 2) Identification of biomarkers and genetic/epigenetic markers for treatment effect and severity of disease, as well as characterization and stratification of early disease 3) Understanding of pain mechanisms in order to optimize the treatment of pain 4) Development and evaluation of strategies to detect, treat and prevent comorbidity 5) To develop and investigate user-friendliness, effect and cost-effectiveness of personalized digital remote follow-up 6) Evaluating the long-term effect, work participation and health economic consequences of various treatment strategies through linking to national registers 7) Health competence, compliance with treatment and eHealth strategies to strengthen the patient's ability to master their illness. The results from the research center are expected to have major benefits for individuals and society. REMEDY is funded by the Norwegian Research Council and the Olav Thon Foundation.