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Sammee Van Arsdale
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Work Experience
N/A
Jan 2017 - Present · 8 years
Arch Health Partners - Palomar Health
N/A
Jan 2014 - Nov 2016 · 2 years and 10 months
Tonbo Biosciences
N/A
Jan 2012 - Jun 2013 · 1 years and 5 months
Company Details
51-200 Employees
What is exciting about the area we work in Epigenomics is the systematic analysis of the global state of gene expression not attributable to mutational changes across the entire genome. Epigenetic mechanisms are affected by external factors including development in utero and in childhood, environmental chemicals, drugs and pharmaceuticals, aging, and diet. Changes to the epigenetic landscape can have a profound impact on health and disease. Precise mapping and measurement of the epigenetic landscape offers the promise of predictive biomarkers of disease development, even before changes in gene expression have taken place. Epigenomics is the “OME” connecting Genomics to Transcriptomics and Proteomics allowing a Multiomics approach to disease research which will result in a higher yield of data that can be aggregated and analyzed to become actionable information. What does Active Motif offer Epigenetic methods and approaches require the use of high-quality antibodies and enzymes that have undergone strict validation criteria. This allows the development of robust assays for use in mechanistic studies, translational medicine, drug discovery and diagnostics. Active Motif’s Product Development Program takes emerging novel techniques, and develops them into innovative products that allow researchers to perform the assays in their own labs as well as feeding into their end to end services pipeline. Active Motif is building a platform based on their patented transposase based technologies to simplify the interrogation of chromatin, the dynamics of histone modifications, chromatin remodeling, DNA methylation, transcription factor binding, as well as short and long range gene regulation by non-coding regulatory regions. Our bioinformatics platform can take the data generated by these techniques and provide powerful insights into the epigenetic changes occurring in disease or in response to drugs.
Year Founded
1999
Social Media
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Industry
Biotechnology Research, Importers-exporters, chemicals, General traders, department and retail stores, Retail & Traders, Importers and exporters, Scientific Research and Development Services, Services
HQ Location
1914 Palomar Oaks Way Ste. 150 Carlsbad, California 92008, US
Keywords
EpigeneticsGenome wide epigenetic servicesChIP SeqTranscription analysisHistone antibodiesDNA methylation analysisGene regulatioLab ServicesLife SciencesLaboratory Equipment
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