The Translational Research Institute for Space Health (TRISH) is a lean, virtual institute empowered by the NASA Human Research Program to solve the challenges of human deep space exploration. TRISH relentlessly pursues and funds novel research to deliver high-impact scientific and technological solutions that advance space health and help humans thrive wherever they explore, in space or on Earth. Led by Baylor College of Medicine's Center for Space Medicine, our consortium leverages partnerships with Caltech and MIT.