The Children’s Hospital Research Institute of Manitoba (CHRIM) is the research division of the Children’s Hospital Foundation of Manitoba. At the institute, more than 270 world-class pediatric medical researchers, technical staff, students, and support staff are involved in nearly $20 million of research and clinical trial activity each year. CHRIM is the first research facility dedicated exclusively to pediatric research in the prairie provinces. CHRIM brings together top researchers from a variety of health disciplines who share a common goal of improving the health of children and youth. By including a wide range of disciplines, CHRIM has the unique ability to look at the overall picture of pediatric health – not just one area. The Institute fosters a collaborative and innovative research environment, offering hope to children and their families as researchers work towards medical breakthroughs and cures for childhood illness. The Children’s Hospital Foundation of Manitoba is the main operating funding source for the Institute. The Foundation invests directly into research by providing core funding for research projects, and provides administrative and infrastructure supports for researchers. With the support of the Foundation and the resources provided by the Institute, CHRIM investigators have more opportunities and better success in applying for external funding.