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Nicole Afacan
Principal Scientist & Group Lead, In Vitro Pharmacology Multispecific Antibody Therapeutics at Zymeworks
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Work Experience
Aug 2017 - Present · 7 years and 4 months
Principal Scientist & Group Lead, In Vitro Pharmacology Multispecific Antibody Therapeutics
Jun 2023 - Present · 1 years and 6 months
Senior Scientist
Jan 2021 - Jun 2023 · 2 years and 5 months
Scientist
Aug 2017 - Dec 2020 · 3 years and 4 months
Company Details
201-500 Employees
Zymeworks (NASDAQ:ZYME) is a clinical-stage biopharmaceutical company dedicated to the development of next-generation multifunctional biotherapeutics. Zymeworks’ suite of therapeutic platforms and its fully integrated drug development engine enable precise engineering of highly differentiated product candidates. Zymeworks’ lead clinical candidate, zanidatamab, is a novel Azymetric™ HER2-targeted bispecific antibody currently being evaluated in multiple Phase 1, Phase 2, and pivotal clinical trials globally as a targeted treatment option for patients with solid tumors that express HER2. Zymeworks’ second product candidate, Zanidatamab Zovodotin (ZW49), is a bispecific antibody-drug conjugate currently in Phase 1 clinical development and combines the unique design and antibody framework of zanidatamab with Zymeworks’ proprietary ZymeLink™ linker-cytotoxin. Zymeworks is also advancing a deep preclinical pipeline in oncology (including immuno-oncology agents) and other therapeutic areas. In addition, its therapeutic platforms are being leveraged through strategic partnerships with nine biopharmaceutical companies.
Year Founded
2003
Social Media
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Industry
Biotechnology Research, Biotechnology research and development, Research and testing, IT, Internet, R&D, Foreign bank representation, Financial and insurance services, Business Services
HQ Location
540 - 1385 West 8th Ave Vancouver, BC V6H 3V9, CA
Keywords
antibody therapeuticsbispecific antibodieseffector function modulationADCBreast CancerGastric Cancerprotein engineeringImmune redirectionand Biliary Tract Cancer
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