Holostem S.r.l. is the first biotechnological company entirely devoted to research, development, manufacture, registration and distribution of Advanced Therapies Medicinal Products (ATMPs) based on cultures of epithelial stem cells both for cell and gene therapy. The main aim of Holostem S.r.l. is to provide therapeutic solutions, based on epithelial stem cell-based, for patients with no alternative therapeutic solutions. Holostem S.r.l. is located in the Centre for Regenerative Medicine "Stefano Ferrari" of the University of Modena and Reggio Emilia.