We are pioneers in surgical navigation and precision healthcare, empowering physicians with safe, real-time, imaging solutions that improve outcomes, lower costs, and reduce radiation exposure for both patients and caregivers in minimally invasive endovascular procedures. Delivering on our commitment to improve quality of life by changing the way healthcare is delivered, our multidisciplinary team of scientists, clinicians, engineers, and software architects has developed the Intra-Operative Positioning System (IOPS™). This mobile and affordable GPS-like 3D vascular navigation system allows for greater surgical precision and control than ever before, improving device placement accuracy, simplifying complex procedures, and potentially decreasing endoleaks and costly secondary interventions. Millions of vascular procedures are performed each year with minimally invasive, endovascular procedures frequently preferred over open surgical repair. Currently, to navigate within vessels physicians rely on x-ray fluoroscopy. This technology has several critical limitations, including lack of soft tissue visualization and exposure to harmful ionizing radiation. IOPS™, which fits directly into existing workflows and operating rooms, eliminates this excessive radiation exposure by creating manipulable 3D models of the relevant anatomy. These intelligent models are created from existing imaging that is already part of the standard of care. Centerline Biomedical, Inc. was founded in 2014 as a spinoff of the Cleveland Clinic to commercialize our innovative vascular navigation technology. With a research, development, and design history rooted in the Clinic’s world-class Lerner Research Institute’s Heart and Vascular Institute, the IOPS™ platform can be further used for predictive modeling, clinical decision support, global healthcare analytics and the education and training of future surgeons and interventionists. See the IOPS™ technology in action: https://youtu.be/U8RL3_UNP8Q