We develop, implement and evaluate evidence-based digital behaviour change interventions that use proven behavioural science to empower people to overcome problem drinking, drug misuse and smoking. Our innovations include three world-firsts in digital healthcare: Computer-assisted therapy that enables recovery from dependence on drugs including opiates and new psychoactive substances Internet-based interventions for substance-involved offenders in prisons that provide essential continuity of care between secure correctional and community settings. Clinically-robust public health interventions that address smoking and problem drinking on a population-wide scale in multiple languages. Our solutions are commissioned across the UK, US and Canada by a wide range of organisations To date, we have delivered clinical interventions to over 100,000 individuals, and evidenced their impact through 35 studies published in peer-reviewed scientific journals.