CureGRIN Foundation is a parent-run charity organization dedicated to improving the lives of people around the world with GRI Disorders (GRIA, GRID, GRIK, and GRIN) and their families through research, education, and support. We work closely with scientists and the medical community to drive patient-centered research that will lead to treatments and cures. GRI Disorders may be rare, but hope should not be! Our goal is simple and bold: To find cures and therapies for people living with GRI disorders caused by variants in GRIA, GRID, GRIK, and GRIN genes. GRI Disorders are part of a larger family of genetic diseases related to ionotropic glutamate receptors. These receptors play an important role in learning and memory as well as other critical biological functions. GRI Disorders are rare genetic conditions with severe life-limiting consequences. Many GRI patients are non-verbal, unable to walk, and many cannot feed or toilet themselves. They often suffer severe and frequent seizures that are not responsive to medical therapies.