The Olivia Newton-John Cancer Research Institute (ONJCRI) is embedded within the Olivia Newton-John Cancer Centre. Our mission is to discover and develop breakthrough therapies to help people live better with cancer or defeat it. Our research laboratories sit alongside patient treatment facilities to optimise collaboration between researchers and clinicians. The integration of laboratory and clinic ensures the rapid translation of scientific discoveries into clinical trials for the development of new cancer treatments. The ONJCRI is a global leader in the development of immunotherapies, targeted therapeutics and personalised cancer medicine. The ONJCRI is the successor to the global Ludwig Cancer Research organisation with a proud track record of a quarter century of collaborative clinical research programs with Austin Health. Much of ONJCRI’s strong foundation is built on the Ludwig Cancer Research legacy, and Ludwig Cancer Research’s ongoing funding to continue translational research projects. Moreover, through the ONJCRI’s exciting partnership with La Trobe University as its School of Cancer Medicine, we play a pivotal role in training Australia’s future generations of medical researchers.