Established in 1917, the University of Zagreb School of Medicine is the oldest educational institution for medical training and research in the South-East Europe. Apart from the vigorous publication activity resulting in 1,323 papers published in high-profile international journals, including 222 co-authored with the renowned members of international research community (mainly from the USA, United Kingdom and Germany), the researchers at the Zagreb School of Medicine successfully participated in a number of international research projects. Over the past six years five projects were financed by the European Framework Program FP5, seven projects by the FP6, and one project has recently been approved for the FP7 financing. Five other projects received support within the framework of COST actions, two within the TEMPUS program, and one in the recently established Croatian-Indian research collaboration. Finally, there is a number of research initiatives and bilateral collaborations between Croatian and international research groups supported by Fogarty International Research Collaboration, Fulbright, DAAD and the Wilhelm von Humboldt Foundation. The University of Zagreb School of Medicine encourages its faculty to participate in international research in the following areas: - basic and clinical neuroscience, including neuroimaging and neurogenomics, pathophysiology of Alzheimer’s disease, - molecular biology, - genomics, proteomics and metabolomics, - bone morphogenic proteins and biological regeneration of tissues, - pharmacogenetics, - transplantation medicine, - hematopoietic malignancies, - congenital metabolic diseases, - clinical endocrinology and diabetes, - public health with environmental medicine.