Compris: Comprehensive Addiction Diagnostics. A Longer Life-Saving View Compris is the only substance use assessment available that offers comprehensive addiction diagnostics and risk stratification consistent with a chronic illness treatment paradigm. Its carefully designed algorithms translate evidence-based lifetime risk and resilience factors, substance use illness acuity and severity, motivation and denial, into the first complete prevention and long-term addiction management guide to also include level of care placement and medication selection/minimum duration. Our online addiction assessment takes 15-20 minutes and is automated to deliver the Compris Profile© to providers within minutes of completion. Compris’ timely needs assessment helps mitigate the ongoing addiction epidemic by: 1) predicting addiction risk to help prevent it, 2) offering providers research-based prevention, treatment, and remission-sustaining guidance, 3) Level of care placement including adjustments for those with varying resilience resources, 4) Supporting increased telehealth treatment access, and 5) Creating an unprecedented research and practice-informing database with machine learning to accelerate our knowledge of how best to treat and manage this devastating chronic illness.