The Technical University of Madrid (UPM) is promoting a unique and cross-cutting postgraduate program between the schools of engineering and architecture, with the ambition to become an international benchmark. The Master in City Sciences is an advanced program that provides a holistic view on the development of the city. Nowadays, the city is the first economic and social engine worldwide. It is the object of interest of the most important companies. Traditional university courses have failed to respond to the urgent demand of professionals with a technical and comprehensive vision of the urban phenomenon. Answering this demand, the MCS program integrates disciplines related with planning, energy, sociology, economics and all the new technologies and infrastructures that are the core of the functioning of the city. Right from the start, students from all nations will be trained in city-related areas both in a theoretical and practical way, in order to achieve a high professional level. MCS is based on real projects that will be approached as case studies. This transdisciplinary approach has made that important international companies are involved in the MCS faculty, in the preparation of the final master thesis and in the possible subsequent employment.