JAMA, published continuously since 1883, is an international peer-reviewed general medical journal. JAMA is a member of the JAMA Network, a consortium of peer-reviewed, general medical and specialty publications. JAMA is the most widely circulated general medical journal in the world, with more than 289,000 recipients of the print journal, more than 1.5 million recipients of electronic tables of contents and alerts, and over 30 million annual visits to the journal's website. JAMA is published 48 times per year in print/online issues, and new articles are published several times a week online. Without any author fees, all research articles are made free access online 6 months after publication on the JAMA website. In addition, the online version is freely available or nearly so to institutions in developing countries through the World Health Organization's HINARI program. Kirsten Bibbins-Domingo, PhD, MD, MAS, is the Editor in Chief of JAMA,. JAMA is a member of the International Committee of Medical Journal Editors, cosponsors the International Congress on Peer Review and Biomedical Publication, and is a member of the African Journal Partnership Project and is partnered with the Malawi Medical Journal. JAMA's key objective is to promote the science and art of medicine and the betterment of the public health. JAMA ISSN 0098-7484 (Print) ISSN 1538-3598 (Online)