Immerse yourself in the best of Panama City at the Best Western Plus Panama Zen Hotel. Among places to stay in Panama City, Panama, no hotel combines our prime location – a few blocks from downtown businesses and attractions – with unique ambiance, modern luxury and state-of-the-art technology. Immediately upon stepping into our lobby, you'll sense what sets us apart from typical hotels in “Ciudad de Panamá.” Our bright, sophisticated lobby is decorated in a Zen style that relaxes and soothes the senses. Settle into bright, spacious rooms teeming with natural light through oversized windows offering views of bustling downtown.