The Laboratório Associado para a Química Verde | Associated Laboratory for Green Chemistry (LAQV@REQUIMTE) is the Portuguese Research Centre for Sustainable Chemistry, a key component of an imperative World Sustainable Development. LAQV was created by researchers from the NOVA University of Lisbon and the University of Porto. In the present configuration, it spreads out from the two main national metropolitan areas of Lisbon and Porto to integrate Aveiro, Coimbra, Évora, Minho, and small sites all over the country. Currently, LAQV embraces 1088 researchers, including 484 PhD holders, who are currently pushing the boundaries of Sustainable Chemistry and Chemical Engineering to provide sustainable and practical solutions for governments, industry, and the general public. Following a vision of a world in which Sustainable Chemistry is used as a powerful and dynamic tool to tackle the challenges of modern life, the mission of LAQV is to initiate, advance, and promote its principles through a multiplicity of research, networking, training, and outreach activities. For that purpose, the thematic lines that guide LAQV researchers are aligned with the Research Agenda of the European Technology Platform for Sustainable Chemistry (SUSCHEM), the United Nations (UN) Sustainable Development Agenda, and the priorities of the European Commission through Horizon Europe.