Regenerative Biologics, Inc. (RBI) was founded in 1982 as the University of Florida Department of Orthopedics Bone Bank by some of the most knowledgeable professionals in the orthopedic community. As tissue donation and transplantation gained greater acceptance, the organization's growth and community services expanded to meet the increasing demand for transplantable tissues. In 2001, after almost twenty years of advancing transplant science as an agency of the University of Florida, the tissue bank became a separate organization. It changed its name to Southeast Tissue Alliance, Inc. (SETA) in 2013, changed its business model to focus on living donor tissue, and became Regenerative Biologics, Inc. RBI is a not-for-profit, 501 (c)3 organization committed to recovering human tissues for transplantation and research. One of the most critical aspects of this process is ensuring that donor families understand tissue donation and are fully supported as they give gifts that change the lives of others.