Arc Institute is a new scientific institution that conducts curiosity-driven basic science and technology development. Headquartered in Palo Alto, California, Arc is a non-profit organization founded on the belief that many important research programs will be enabled by new academic models. Arc operates in partnership with Stanford University, UCSF, and UC Berkeley. As individuals, Arc researchers collaborate across diverse disciplines to study complex diseases, including cancer, neurodegeneration, and immune dysfunction. As an organization, Arc strives to enable long-term research agendas by betting on people rather than projects, and making it easier to invent and deploy new technologies at scale. Together, our mission is to accelerate scientific progress, understand the root causes of disease, and narrow the gap between discoveries and impact on patients.