The Select Milano Committee has been working for a new set of Anglo-Italian relations since January 2013, when British Prime Minister David Cameron promised to call a Leave/Remain referendum in the UK. In light of the Brexit, Select Milano has developed the idea of launching an economic diplomacy initiative to design a new economic paradigm and a new framework of commercial liaisons between Italy and the United Kingdom, centred around Milan – as the economic capital of Italy – and the City of London – as the governing body of the Square Mile, the preeminent world financial services centre. Select Milano was established with the purpose of building a permanent bridge between London and Milan and to relocate in Milan those financial markets, which for purely regulatory reasons can no longer be housed in the City of London. Select Milano aims at promoting the set-up of the business district “Milano.Distretto:Affari” and wants to engage the central and local governments to bring about legislative measures capable to mitigate the country risk. Select Milano invites Italy to work as a system. The city of Milan is credible to be the financial capital of the Eurozone, and a sister financial citadel of the City of London, all at the outcome of a shared agenda with the United Kingdom.