The Western Australian Marine Science Institution (WAMSI) is a collaboration of state and federal government and academic science organisations working together to provide independent marine research for the benefit of the environment, the community and the Blue Economy. Research covers climate change, marine life, ocean geology, fishing, oceanography, biodiversity and social issues. WAMSI research has made unique new discoveries, strengthened previous knowledge and developed new tools or applied existing national or global models to the Western Australian (WA) context. We have a new knowledge and enhanced understanding of the WA marine estate and its biological resources. The roles of oceanic and atmospheric forces in shaping the climate of WA and effects on key fisheries are now better understood. New predictive models and decision support tools have been developed for direct application to specific locations. This knowledge and the new tools being crucial for management of marine protected areas, fisheries, tourism, marine based industries and coastal development now and in the future. World class research has improved our understanding of natural climate variability and predictions of longer term climate change for the WA marine environment. The WA marine science community now has an integrated and coordinated approach to complex research issues to inform management and industry decision-making.