Oxford Cryosystems is a market-leading manufacturer of specialist cryogenic instrumentation and software in the area of X-ray Crystallography. It also manufactures a range of Gifford McMahon Cryocoolers, The roots of the company lie in the design and manufacture of the original Cryostream Cooler in 1985, which immediately became the system of choice for cooling samples in X-ray diffraction experiments. The range of products for use in sample cooling has expanded over the last twenty-five years to include liquid-free systems, helium coolers and specially adapted systems for use with powder samples, and today the company is considered to be the global market leader in X-ray diffraction sample cooling. A complementary range of products is our “Coolstar” range of Gifford McMahon Cryocoolers, used in applications as diverse as vacuum pumps and astrophysics. These single and two-stage coolers are well-known for their compact size and ease of use, allowing them to be easily incorporated into OEM applications. The final group of products is produced by our in-house software team. Our software brand, Crystallographica, offers both free software for crystallography teaching as well as one of the best-known search-match programs.