Our team at the ARC Centre of Excellence in Optical Microcombs for Breakthrough Science (COMBS) is using technology – called the optical frequency comb – to drive society-wide transformations in the fields of biomedical imaging, communications, precision measurement and astronomy. Optical frequency combs are still generally confined to the most advanced science labs due to their size and complexity, however our team at COMBS aims to transform these systems into light-powered chips the size of a fingernail. We will do this through partnering with scientific and industrial end-users to create new approaches and solutions in the biomedical imaging, communications, precision measurement and astronomy. This Centre is funded by the Australian Government through the Australian Research Council.