Lccrh Laboratoire Cellules Circulantes Rares Humaines

Scientific and technical expertise in the exploration of residual disease in oncology: Identification and characterization of circulating tumor cells (CTCs: Real-time liquid biopsy of the tumor and/or metastases). Skills - Isolation, enumeration and molecular & phenotypic characterizations of CTCs (various biological fluids: blood, bone marrow, cerebrospinal fluid) - solid cancers - Specialized biology analyses: CellSearch® system, EPISPOT technique CellCollector®, flow cytometry Quantitative RT-PCR on single cells - In vitro culture of CTCs isolated from the blood of patients - Understanding the mechanisms of tumor dissemination