Jiangsu Xiansheng Pharmaceutical

Simcere was founded on March 28, 1995 with an enterprise mission to "discover and develop high-quality medicines for patients." Since its inception, we have grown from a registered capital of 2.78 million to total assets of over 3 billion yuan, from a few dozen people to an R&D-driven pharmaceutical enterprise with more than 3,000 talents, and from an annual tax of less than a million to about 500 million yuan. We have ranked among "the top 100 Chinese Pharmaceutical Companies" for consecutive years, and our growth goes beyond the numbers.To fulfill our dream, we have progressed through a string of strategic options, including but not limited to the development of first generic products, merger and acquisition, the build-up of research institute, an alliance with multinational corporations, and innovative research mechanisms. At present, these efforts are bearing fruits:In 2009, our montmorillonite powder product successfully passed EU GMP certification and started exporting to Europe, a milestone for Made in Simcere for global markets. Currently, we are actively implementing cGMP and EUGMP to transform all of our small molecule manufacture sites to comply with international standards. In recent years, Simcere has established high-quality international cooperation through various partnership models. For example, we partnered with American Apexigen Company to develop an innovative anti-VEGF humanized monoclonal antibody in China. Together with Bristol-Myers Squibb, we are conducting Phase III trial for abatacept, a monoclonal antibody for treatment of rheumatoid arthritis, and so forth. These partnerships are a powerful testament to the fact that Chinese pharmaceutical companies can collaborate with multinational corporations to scale down R&D cost and accelerate R&D innovation in China. The Ministry of Science and Technology recognized our Company as an International Scientific and Technological Cooperation Base.We now own over 50 products that cover Oncology, Cardiovascular and Cerebrovascular, Anti-infection, Rheumatology and other therapeutic areas. We have three products (Endostar, Sinofuan, Iremod) that were the first-to-launch in the world, and six products(BICUNAILINANTINEYEQINGJIEBAISHUNewanti) that were the first-in-class in China. Since 2007, we have submitted over 200 domestic and PCT patent applications. Over 10 innovative drugs are being studied in clinical trials, which will broaden our current marketed product portfolio. In 2015, the Ministry of Science and Technology designated one of our laboratories as the national key laboratory for translational medicine and innovative drugs. Simcere ranks among the Top 10 Chinese Companies in Pharmaceutical Innovation in recent years.