AGO Alliance (formerly AGO2) is a Swiss-based non-profit dedicated to advancing the development of therapeutics for Argonaute syndromes (AGO1, AGO2 genes), bringing affected families together, and educating.
The Argonaute genes play a key role in the regulation of other genes via RNA interference. The syndromes associated with mutations in AGO1 and AGO2 were discovered only in 2021 and 2020, respectively. Affected children may suffer from speech & walking problems, intellectual disability, heart defects and seizures.
We are a volunteer-led organisation and have partners in multiple countries to enable tax-deductible donations.